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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HUWE1
All Species:
13.64
Human Site:
S1692
Identified Species:
37.5
UniProt:
Q7Z6Z7
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z6Z7
NP_113584.3
4374
481891
S1692
V
P
R
L
N
K
N
S
K
N
S
N
G
Q
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088987
4374
481661
S1692
V
P
R
L
N
K
N
S
K
N
S
N
G
Q
E
Dog
Lupus familis
XP_538052
4375
482124
S1692
V
P
R
L
N
K
N
S
K
N
S
N
G
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMY8
4377
482644
S1692
V
P
R
L
S
K
N
S
K
S
S
N
G
Q
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923899
4360
479137
P1692
V
Q
R
V
P
R
I
P
K
A
T
K
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573059
5146
556842
N1833
S
E
A
I
T
S
L
N
N
P
V
A
L
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_500284
4177
465393
C1654
E
H
L
I
A
E
I
C
G
E
D
L
K
N
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GY23
3681
404981
I1216
Q
S
Q
V
L
D
V
I
L
P
I
W
N
H
P
Baker's Yeast
Sacchar. cerevisiae
Q03280
3268
374166
V803
E
D
Y
A
F
M
D
V
M
K
V
L
N
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
98.7
N.A.
97.7
N.A.
N.A.
N.A.
N.A.
N.A.
81.6
N.A.
33.7
N.A.
26.2
N.A.
Protein Similarity:
100
N.A.
99.7
99.1
N.A.
98.6
N.A.
N.A.
N.A.
N.A.
N.A.
88.4
N.A.
48.4
N.A.
44.3
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.1
38.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
12
0
0
0
0
12
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
12
12
0
0
0
12
0
0
12
0
% D
% Glu:
23
12
0
0
0
12
0
0
0
12
0
0
0
0
45
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
0
45
12
0
% G
% His:
0
12
0
0
0
0
0
0
0
0
0
0
0
23
0
% H
% Ile:
0
0
0
23
0
0
23
12
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
45
0
0
56
12
0
12
12
0
12
% K
% Leu:
0
0
12
45
12
0
12
0
12
0
0
23
12
0
0
% L
% Met:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
34
0
45
12
12
34
0
45
23
12
0
% N
% Pro:
0
45
0
0
12
0
0
12
0
23
0
0
0
0
12
% P
% Gln:
12
12
12
0
0
0
0
0
0
0
0
0
0
45
12
% Q
% Arg:
0
0
56
0
0
12
0
0
0
0
0
0
0
0
0
% R
% Ser:
12
12
0
0
12
12
0
45
0
12
45
0
12
0
12
% S
% Thr:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% T
% Val:
56
0
0
23
0
0
12
12
0
0
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _